NeuroMabSeq

Mouse Light Chain Results

Sequence: 1 -- Star rating: ☆-0.60

AGCATCAGACAGGCTGGGCAGCAAGATGGAATCACAGACCCAGGTCCTCATGTTTCTTCTGCTCTGGGTATCTGGTGCCTGTGCAGACATTGTGATGACACAGTCTCCATCCTCCCTGGCTATGTCAGTAGGACAGAAGGTCACTATGAGCTGCAAGTCCAGTCAGAGCCTTTTAAATAGTAGCAATCAAAAGAACTATTTGGCCTGGTACCAGCAGAAACCAGGACAGTCTCCTAAACTTCTGGTATACTTTGCATCCACTAGGGAATCTGGGGTCCCTGATCGCTTCATAGGCAGTGGATCTGGGACAGATTTCACTCTTACCATCAGCAGTGTGCAGGCTGAAGACCTGGCAGATTACTTCTGTCAGCAACATTATAGCACTCCATTCACGTTCGGCTCGGGGACAAAGTTGGAAATAAAACGGGCT

Sequence 1 corresponding to IMGT amino acids 1-127:

GACATTGTGATGACACAGTCTCCATCCTCCCTGGCTATGTCAGTAGGACAGAAGGTCACTATGAGCTGCAAGTCCAGTCAGAGCCTTTTAAATAGTAGCAATCAAAAGAACTATTTGGCCTGGTACCAGCAGAAACCAGGACAGTCTCCTAAACTTCTGGTATACTTTGCATCCACTAGGGAATCTGGGGTCCCTGATCGCTTCATAGGCAGTGGATCTGGGACAGATTTCACTCTTACCATCAGCAGTGTGCAGGCTGAAGACCTGGCAGATTACTTCTGTCAGCAACATTATAGCACTCCATTCACGTTCGGCTCGGGGACAAAGTTGGAAATAAAA

Sequencing Info ☆ Scoring Info Amino Acid Information Blat Sequence

IMGT amino acid positions:

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	101	102	103	104	105	106	107	108	109	110	111	112	113	114	115	116	117	118	119	120	121	122	123	124	125	126	127
D	I	V	M	T	Q	S	P	S	S	L	A	M	S	V	G	Q	K	V	T	M	S	C	K	S	S	Q	S	L	L	N	S	S	N	Q	K	N	Y	L	A	W	Y	Q	Q	K	P	G	Q	S	P	K	L	L	V	Y	F	A	-	-	-	-	-	-	-	S	T	R	E	S	G	V	P	-	D	R	F	I	G	S	G	-	-	S	G	T	D	F	T	L	T	I	S	S	V	Q	A	E	D	L	A	D	Y	F	C	Q	Q	H	Y	S	-	-	-	-	T	P	F	T	F	G	S	G	T	K	L	E	I	K
LFR1																										CDR-L1												LFR2																	CDR-L2										LFR3																																							CDR-L3													LFR4

Residues	Region	Sequence Fragment	Length	Max Index Range
1-26	LFR1	DIVMTQSPSSLAMSVGQKVTMSCKSS	26	26
27-38	CDR-L1	QSLLNSSNQKNY	12	12
39-55	LFR2	LAWYQQKPGQSPKLLVY	17	17
56-65	CDR-L2	FAS	3	10
66-104	LFR3	TRESGVPDRFIGSGSGTDFTLTISSVQAEDLADYFC	36	39
105-117	CDR-L3	QQHYSTPFT	9	13
118-128	LFR4	FGSGTKLEIK	10	10

Mouse Heavy Chain Results

Sequence: 1 -- Star rating: ☆1.30

GACAGAGGAGGCCAGTCCTGGATTTGAGTTCCTCACATTCAGTGATGAGCACTGAACACAGACACCTCACCATGAACTTCGGGTTCAGCTTGATTTTCCTTGTCCTTGTTTTAAAAGGTGTCCAGTGTGAAGTGAAGCTGGTGGAGTCTGGGGGAGGCTTAGTGAAGCCTGGAGGGTCCCTGAAAGTCTCCTGTGTAGCCTCTGGATTCACTTTCAGTAGCTCTGCCATGTCTTGGGTTCGCCAGACTCTAGAGAAGAGGCTGGAGTGGGTCGCATCCATTAGTAGTGTTGGTAGTGTCTACTATCCAGACAGTGTGAAGGGCCGATTCACCATCTCCAGAGATAATGCCAGGAACATCCTGTACCTGCAAATGAGCAGTCTGAGGTCTGAGGACACGGCCATGTATTACTGTGCAAGAGGCAAGAAATATGGTAACTACCTTTACTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCTTCAG

Sequence 1 corresponding to IMGT amino acids 1-128:

GAAGTGAAGCTGGTGGAGTCTGGGGGAGGCTTAGTGAAGCCTGGAGGGTCCCTGAAAGTCTCCTGTGTAGCCTCTGGATTCACTTTCAGTAGCTCTGCCATGTCTTGGGTTCGCCAGACTCTAGAGAAGAGGCTGGAGTGGGTCGCATCCATTAGTAGTGTTGGTAGTGTCTACTATCCAGACAGTGTGAAGGGCCGATTCACCATCTCCAGAGATAATGCCAGGAACATCCTGTACCTGCAAATGAGCAGTCTGAGGTCTGAGGACACGGCCATGTATTACTGTGCAAGAGGCAAGAAATATGGTAACTACCTTTACTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCTTCA

Sequencing Info ☆ Scoring Info Amino Acid Information Blat Sequence

IMGT amino acid positions:

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	101	102	103	104	105	106	107	108	109	110	111	111	112	112	112	113	114	115	116	117	118	119	120	121	122	123	124	125	126	127	128
E	V	K	L	V	E	S	G	G	-	G	L	V	K	P	G	G	S	L	K	V	S	C	V	A	S	G	F	T	F	-	-	-	-	S	S	S	A	M	S	W	V	R	Q	T	L	E	K	R	L	E	W	V	A	S	I	S	S	V	-	-	-	G	S	V	Y	Y	P	D	S	V	K	-	G	R	F	T	I	S	R	D	N	A	R	N	I	L	Y	L	Q	M	S	S	L	R	S	E	D	T	A	M	Y	Y	C	A	R	G	K	K	Y	G	N	Y	L	Y	Y	A	M	D	Y	W	G	Q	G	T	S	V	T	V	S	S
HFR1																										CDR-H1												HFR2																	CDR-H2										HFR3																																							CDR-H3																HFR4

Residues	Region	Sequence Fragment	Length	Max Index Range
1-26	HFR1	EVKLVESGGGLVKPGGSLKVSCVAS	25	26
27-38	CDR-H1	GFTFSSSA	8	12
39-55	HFR2	MSWVRQTLEKRLEWVAS	17	17
56-65	CDR-H2	ISSVGSV	7	10
66-104	HFR3	YYPDSVKGRFTISRDNARNILYLQMSSLRSEDTAMYYC	38	39
105-117	CDR-H3	ARGKKYGNYLYYAMDY	16	16
118-128	HFR4	WGQGTSVTVSS	11	11

Entry: N447/24.8

Protein Target: Kv11.3 K+ channel

Category: NeuroMab mAbs

Mouse Light Chain Results

Mouse Heavy Chain Results