NeuroMabSeq

Mouse Light Chain Results

Sequence: 1 -- Star rating: ☆3.05

ATCCTCTCTTCTAGCTCTCAGAGATGGAGACAGACACACTCCTGCTATGGGTGCTGCTGCTCTGGGTTCCAGGTTCCACTGGTGACATTGTGCTGACACAGTCTCCTGCTTCCTTAGCTGTATCTCTGGGGCAGAGGGCCACCATCTCATGCAGGGCCAGCCAAAGTGTCAGTACATCTAGCTATAGTTATATGCACTGGTACCAACAGAAGCCAGGACAGCCACCCAAACTCCTCATCAAGTATGCATCCAACCTAGAATCTGGGGTCCCTGCCAGGTTCAGTGGCAGTGGGTCTGGGTCAGACTTCACCCTCAACATCCATCCTGTGGAGGAGGAGGATACTGCAACATATTACTGTCAGCACAGTTGGGAGATTCCGCACACGTTCGGAGGGGGGACCAAGCTGGAAATAAAACGGGCT

Sequence 1 corresponding to IMGT amino acids 1-127:

GACATTGTGCTGACACAGTCTCCTGCTTCCTTAGCTGTATCTCTGGGGCAGAGGGCCACCATCTCATGCAGGGCCAGCCAAAGTGTCAGTACATCTAGCTATAGTTATATGCACTGGTACCAACAGAAGCCAGGACAGCCACCCAAACTCCTCATCAAGTATGCATCCAACCTAGAATCTGGGGTCCCTGCCAGGTTCAGTGGCAGTGGGTCTGGGTCAGACTTCACCCTCAACATCCATCCTGTGGAGGAGGAGGATACTGCAACATATTACTGTCAGCACAGTTGGGAGATTCCGCACACGTTCGGAGGGGGGACCAAGCTGGAAATAAAA

Sequencing Info ☆ Scoring Info Amino Acid Information Blat Sequence

IMGT amino acid positions:

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	101	102	103	104	105	106	107	108	109	110	111	112	113	114	115	116	117	118	119	120	121	122	123	124	125	126	127
D	I	V	L	T	Q	S	P	A	S	L	A	V	S	L	G	Q	R	A	T	I	S	C	R	A	S	Q	S	V	S	T	-	-	S	S	Y	S	Y	M	H	W	Y	Q	Q	K	P	G	Q	P	P	K	L	L	I	K	Y	A	-	-	-	-	-	-	-	S	N	L	E	S	G	V	P	-	A	R	F	S	G	S	G	-	-	S	G	S	D	F	T	L	N	I	H	P	V	E	E	E	D	T	A	T	Y	Y	C	Q	H	S	W	E	-	-	-	-	I	P	H	T	F	G	G	G	T	K	L	E	I	K
LFR1																										CDR-L1												LFR2																	CDR-L2										LFR3																																							CDR-L3													LFR4

Residues	Region	Sequence Fragment	Length	Max Index Range
1-26	LFR1	DIVLTQSPASLAVSLGQRATISCRAS	26	26
27-38	CDR-L1	QSVSTSSYSY	10	12
39-55	LFR2	MHWYQQKPGQPPKLLIK	17	17
56-65	CDR-L2	YAS	3	10
66-104	LFR3	NLESGVPARFSGSGSGSDFTLNIHPVEEEDTATYYC	36	39
105-117	CDR-L3	QHSWEIPHT	9	13
118-128	LFR4	FGGGTKLEIK	10	10

Mouse Heavy Chain Results

Sequence: 1 -- Star rating: ☆3.70

AGCTCTGACAGAGGAGCCAAGCCCTGGATTCCCAGGTCCTCACATTCAGTGATCAGCACTGAACACAGACCACTCACCATGGACTCCAGGCTCAATTTAGTTTTCCTTGTCCTTATTTTAAAAGGTGTCCAGTGTGATGTGCAGCTGGTGGAGTCTGGGGGAGGCTTAGTGCAGCCTGGAGGGTCCCGGAAACTCTCCTGTGCAGCCTCTGGATTCACTTTCAGTAGTTTTGGAATGCACTGGGTTCGTCAGGCTCCAGAGAAGGGGCTGGAGTGGGTCGCATACATTAGTAGTGGCAGTAGTACCATCTACTATGCAGACACAGTGAAGGGCCGATTCACCATCTCCAGAGACAATCCCAAGAACACCCTGTTCCTGCAAATGACCAGTCTAAGGTCTGAGGACACGGCCATGTATTACTGTACAAGATCGGATATTACGGTAGTGGGGGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG

Sequence 1 corresponding to IMGT amino acids 1-128:

GATGTGCAGCTGGTGGAGTCTGGGGGAGGCTTAGTGCAGCCTGGAGGGTCCCGGAAACTCTCCTGTGCAGCCTCTGGATTCACTTTCAGTAGTTTTGGAATGCACTGGGTTCGTCAGGCTCCAGAGAAGGGGCTGGAGTGGGTCGCATACATTAGTAGTGGCAGTAGTACCATCTACTATGCAGACACAGTGAAGGGCCGATTCACCATCTCCAGAGACAATCCCAAGAACACCCTGTTCCTGCAAATGACCAGTCTAAGGTCTGAGGACACGGCCATGTATTACTGTACAAGATCGGATATTACGGTAGTGGGGGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCA

Sequencing Info ☆ Scoring Info Amino Acid Information Blat Sequence

IMGT amino acid positions:

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	101	102	103	104	105	106	107	108	109	110	111	112	113	114	115	116	117	118	119	120	121	122	123	124	125	126	127	128
D	V	Q	L	V	E	S	G	G	-	G	L	V	Q	P	G	G	S	R	K	L	S	C	A	A	S	G	F	T	F	-	-	-	-	S	S	F	G	M	H	W	V	R	Q	A	P	E	K	G	L	E	W	V	A	Y	I	S	S	G	-	-	S	S	T	I	Y	Y	A	D	T	V	K	-	G	R	F	T	I	S	R	D	N	P	K	N	T	L	F	L	Q	M	T	S	L	R	S	E	D	T	A	M	Y	Y	C	T	R	S	D	I	T	V	V	G	A	M	D	Y	W	G	Q	G	T	S	V	T	V	S	S
HFR1																										CDR-H1												HFR2																	CDR-H2										HFR3																																							CDR-H3													HFR4

Residues	Region	Sequence Fragment	Length	Max Index Range
1-26	HFR1	DVQLVESGGGLVQPGGSRKLSCAAS	25	26
27-38	CDR-H1	GFTFSSFG	8	12
39-55	HFR2	MHWVRQAPEKGLEWVAY	17	17
56-65	CDR-H2	ISSGSSTI	8	10
66-104	HFR3	YYADTVKGRFTISRDNPKNTLFLQMTSLRSEDTAMYYC	38	39
105-117	CDR-H3	TRSDITVVGAMDY	13	13
118-128	HFR4	WGQGTSVTVSS	11	11

Entry: N385/24.2.4

Protein Target: Beta1-spectrin

Category: Non-NeuroMab mAbs

Mouse Light Chain Results

Mouse Heavy Chain Results