NeuroMabSeq

Mouse Light Chain Results

Sequence: 1 -- Star rating: ☆4.97 -- Verified by Cloning: ✅

ACTCAAGACTTTTTGTATCAAGTTCTCAGAATGAGGTGCCTAGCTGAGTTCCTGGGGCTGCTTGTGCTCTGGATCCCTGGAGCCATTGGGGATATTGTGATGACTCAGGATGCACCCTCTGTACCTGTCATTCCTGGAGAGTCAGCATCCATCTCCTGCAGGTCTAGTAAGAGTCTCCTGCATAGTAATGGCAACACTTACTTATATTGGTTCCTGCAGAGGCCAGGCCAGTCTCCTCAGCTCCTGATATTTCGGATGTCCAACCTTGCCTCAGGAGTCCCAGACAGGTTCAGTGGCAGTGGGTCAGGAACTACTTTCACACTGAGAATCAGTAGAGTGGAGGCTGAGGATGTGGGTGTTTATTACTGTATGCAACATCTAGAATATCCTTTCACGTTCGGTGCTGGGACCAAGCTGGAGCTGAAACGGGCT

Sequence 1 corresponding to IMGT amino acids 1-127:

GATATTGTGATGACTCAGGATGCACCCTCTGTACCTGTCATTCCTGGAGAGTCAGCATCCATCTCCTGCAGGTCTAGTAAGAGTCTCCTGCATAGTAATGGCAACACTTACTTATATTGGTTCCTGCAGAGGCCAGGCCAGTCTCCTCAGCTCCTGATATTTCGGATGTCCAACCTTGCCTCAGGAGTCCCAGACAGGTTCAGTGGCAGTGGGTCAGGAACTACTTTCACACTGAGAATCAGTAGAGTGGAGGCTGAGGATGTGGGTGTTTATTACTGTATGCAACATCTAGAATATCCTTTCACGTTCGGTGCTGGGACCAAGCTGGAGCTGAAA

Sequencing Info ☆ Scoring Info Amino Acid Information Blat Sequence

IMGT amino acid positions:

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	101	102	103	104	105	106	107	108	109	110	111	112	113	114	115	116	117	118	119	120	121	122	123	124	125	126	127
D	I	V	M	T	Q	D	A	P	S	V	P	V	I	P	G	E	S	A	S	-	I	S	C	R	S	S	K	S	L	L	H	-	S	N	G	N	T	Y	L	Y	W	F	L	Q	R	P	G	Q	S	P	Q	L	L	I	F	R	-	-	-	-	-	-	-	M	S	N	L	A	S	G	V	P	-	D	R	F	S	G	S	G	-	-	S	G	T	T	F	T	L	R	I	S	R	V	E	A	E	D	V	G	V	Y	Y	C	M	Q	H	L	-	-	-	E	Y	P	F	T	F	G	A	G	T	K	L	E	L	K
LFR1																										CDR-L1												LFR2																	CDR-L2										LFR3																																							CDR-L3													LFR4

Residues	Region	Sequence Fragment	Length	Max Index Range
1-26	LFR1	DIVMTQDAPSVPVIPGESASISCRS	25	26
27-38	CDR-L1	SKSLLHSNGNT	11	12
39-55	LFR2	YLYWFLQRPGQSPQLLI	17	17
56-65	CDR-L2	FRM	3	10
66-104	LFR3	SNLASGVPDRFSGSGSGTTFTLRISRVEAEDVGVYY	36	39
105-117	CDR-L3	CMQHLEYPFT	10	13
118-128	LFR4	FGAGTKLELK	10	10

Mouse Heavy Chain Results

Sequence: 1 -- Star rating: ☆5.00 -- Verified by Cloning: ✅

AAAACATGAGATCACAGTTCTCTCTACAGTTACTGAGCACACAGGACCTCACCATGGGATGGAGCTATATCATCCTCTTTTTGGTAGCAACAGCTACAGATGTCCACTCCCAGGTCCAACTGCAGCAGCCTGGGGCTGAACTGGTGAAGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACCAGTTACTGGATGCACTGGTTGAAGCAGAGGCCTGGACAAGGCCTTGAGTGGATTGGAGAGATTAATCCTAACAACGGTCGTACTAATAACAATGAGAAGTTCAGGAGCAAGGCCACCCTGACTGTAGACAGATCCTCCAGCACAGCCTATTTGCAACTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTCCTGTGCAAGATCGGTCTACTATGACCCCTACATCTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG

Sequence 1 corresponding to IMGT amino acids 1-128:

CAGGTCCAACTGCAGCAGCCTGGGGCTGAACTGGTGAAGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACCAGTTACTGGATGCACTGGTTGAAGCAGAGGCCTGGACAAGGCCTTGAGTGGATTGGAGAGATTAATCCTAACAACGGTCGTACTAATAACAATGAGAAGTTCAGGAGCAAGGCCACCCTGACTGTAGACAGATCCTCCAGCACAGCCTATTTGCAACTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTCCTGTGCAAGATCGGTCTACTATGACCCCTACATCTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCA

Sequencing Info ☆ Scoring Info Amino Acid Information Blat Sequence

IMGT amino acid positions:

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	101	102	103	104	105	106	107	108	109	110	111	112	113	114	115	116	117	118	119	120	121	122	123	124	125	126	127	128
Q	V	Q	L	Q	Q	P	G	A	-	E	L	V	K	P	G	A	S	V	K	L	S	C	K	A	S	G	Y	T	F	-	-	-	-	T	S	Y	W	M	H	W	L	K	Q	R	P	G	Q	G	L	E	W	I	G	E	I	N	P	N	-	-	N	G	R	T	N	N	N	E	K	F	R	-	S	K	A	T	L	T	V	D	R	S	S	S	T	A	Y	L	Q	L	S	S	L	T	S	E	D	S	A	V	Y	S	C	A	R	S	V	Y	Y	D	P	Y	I	F	D	Y	W	G	Q	G	T	T	L	T	V	S	S
HFR1																										CDR-H1												HFR2																	CDR-H2										HFR3																																							CDR-H3													HFR4

Residues	Region	Sequence Fragment	Length	Max Index Range
1-26	HFR1	QVQLQQPGAELVKPGASVKLSCKAS	25	26
27-38	CDR-H1	GYTFTSYW	8	12
39-55	HFR2	MHWLKQRPGQGLEWIGE	17	17
56-65	CDR-H2	INPNNGRT	8	10
66-104	HFR3	NNNEKFRSKATLTVDRSSSTAYLQLSSLTSEDSAVYSC	38	39
105-117	CDR-H3	ARSVYYDPYIFDY	13	13
118-128	HFR4	WGQGTTLTVSS	11	11

Entry: L71/5.5

Protein Target: Kv1.4 K+ channel

Category: NeuroMab mAbs

Mouse Light Chain Results

Mouse Heavy Chain Results