NeuroMabSeq

Mouse Light Chain Results

Sequence: 1 -- Star rating: ☆2.96 -- Verified by Cloning: ✅

GAAGCATTCTCTCTTCCAGTTCTCAGAGATGGAGAAAGACACACTCCTGCTATGGGTCCTGCTTCTCTGGGTTCCAGGTTCCACAGGTGACATTGTGCTGACCCAATCTCCAGCTTCTTTGGCTGTGTCTCTAGGGCAGAGGGCCACCATCTCCTGCAGAGCCAGCGAAAGTGTTGATAATTATGGCATTAGTTTTATGAACTGGTTCCAACAGAAACCAGGACAGCCACCCAAACTCCTCATCTATGCTGCATCCAACCAAGGATCCGGGGTCCCTGCCAGGTTTAGTGGCAGTGGGTCTGGGACAGACTTCAGCCTCAACATCCATCCTATGGAGGAGGATGATACTGCAATGTATTTCTGTCAGCAAAGTAAGGAGGTTCCGTGGACGTTCGGTGGAGGCACCAAGCTGGAAATCAAACGGGCT

Sequence 1 corresponding to IMGT amino acids 1-127:

GACATTGTGCTGACCCAATCTCCAGCTTCTTTGGCTGTGTCTCTAGGGCAGAGGGCCACCATCTCCTGCAGAGCCAGCGAAAGTGTTGATAATTATGGCATTAGTTTTATGAACTGGTTCCAACAGAAACCAGGACAGCCACCCAAACTCCTCATCTATGCTGCATCCAACCAAGGATCCGGGGTCCCTGCCAGGTTTAGTGGCAGTGGGTCTGGGACAGACTTCAGCCTCAACATCCATCCTATGGAGGAGGATGATACTGCAATGTATTTCTGTCAGCAAAGTAAGGAGGTTCCGTGGACGTTCGGTGGAGGCACCAAGCTGGAAATCAAA

Sequencing Info ☆ Scoring Info Amino Acid Information Blat Sequence

IMGT amino acid positions:

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	101	102	103	104	105	106	107	108	109	110	111	112	113	114	115	116	117	118	119	120	121	122	123	124	125	126	127
D	I	V	L	T	Q	S	P	A	S	L	A	V	S	L	G	Q	R	A	T	I	S	C	R	A	S	E	S	V	D	N	-	-	Y	G	I	S	F	M	N	W	F	Q	Q	K	P	G	Q	P	P	K	L	L	I	Y	A	A	-	-	-	-	-	-	-	S	N	Q	G	S	G	V	P	-	A	R	F	S	G	S	G	-	-	S	G	T	D	F	S	L	N	I	H	P	M	E	E	D	D	T	A	M	Y	F	C	Q	Q	S	K	E	-	-	-	-	V	P	W	T	F	G	G	G	T	K	L	E	I	K
LFR1																										CDR-L1												LFR2																	CDR-L2										LFR3																																							CDR-L3													LFR4

Residues	Region	Sequence Fragment	Length	Max Index Range
1-26	LFR1	DIVLTQSPASLAVSLGQRATISCRAS	26	26
27-38	CDR-L1	ESVDNYGISF	10	12
39-55	LFR2	MNWFQQKPGQPPKLLIY	17	17
56-65	CDR-L2	AAS	3	10
66-104	LFR3	NQGSGVPARFSGSGSGTDFSLNIHPMEEDDTAMYFC	36	39
105-117	CDR-L3	QQSKEVPWT	9	13
118-128	LFR4	FGGGTKLEIK	10	10

Mouse Heavy Chain Results

Sequence: 1 -- Star rating: ☆4.07 -- Verified by Cloning: ✅

AAAACATGAGATCACTGTTCTCTCTACAGTTACTGAGCACACAGGACCTCACCATGGGATGGAGTTGTATCATCCTCTTCTTGGTAGCAACAGCTACAGGTGTCCACTCCCAGGTGCAACTGCAGCAGCCTGGGGCTGAGCTGGTGAAGCCTGGGGCCTCACTGAAGATGTCCTGCAAGGCTTCTGGCTATACATTTACCAGTTACAATCTGCACTGGGTAAAGCAGACACCTGGACAGGACCTGGAATGGATTGGAGCTATTTATCCAGGAAATGGTGATACTTCCTACAATCAGAAGTTCAAAGGCAAGGCCACATTGACTGTAGACAAATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTACTGTGCAAGATTGGGGTTACGACGGGGCTTCGATGTCTGGGGCGCAGGGACCACGGTCACCGTCTCCTCAG

Sequence 1 corresponding to IMGT amino acids 1-128:

CAGGTGCAACTGCAGCAGCCTGGGGCTGAGCTGGTGAAGCCTGGGGCCTCACTGAAGATGTCCTGCAAGGCTTCTGGCTATACATTTACCAGTTACAATCTGCACTGGGTAAAGCAGACACCTGGACAGGACCTGGAATGGATTGGAGCTATTTATCCAGGAAATGGTGATACTTCCTACAATCAGAAGTTCAAAGGCAAGGCCACATTGACTGTAGACAAATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTACTGTGCAAGATTGGGGTTACGACGGGGCTTCGATGTCTGGGGCGCAGGGACCACGGTCACCGTCTCCTCA

Sequencing Info ☆ Scoring Info Amino Acid Information Blat Sequence

IMGT amino acid positions:

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	101	102	103	104	105	106	107	108	109	110	111	112	113	114	115	116	117	118	119	120	121	122	123	124	125	126	127	128
Q	V	Q	L	Q	Q	P	G	A	-	E	L	V	K	P	G	A	S	L	K	M	S	C	K	A	S	G	Y	T	F	-	-	-	-	T	S	Y	N	L	H	W	V	K	Q	T	P	G	Q	D	L	E	W	I	G	A	I	Y	P	G	-	-	N	G	D	T	S	Y	N	Q	K	F	K	-	G	K	A	T	L	T	V	D	K	S	S	S	T	A	Y	M	Q	L	S	S	L	T	S	E	D	S	A	V	Y	Y	C	A	R	L	G	L	R	-	-	R	G	F	D	V	W	G	A	G	T	T	V	T	V	S	S
HFR1																										CDR-H1												HFR2																	CDR-H2										HFR3																																							CDR-H3													HFR4

Residues	Region	Sequence Fragment	Length	Max Index Range
1-26	HFR1	QVQLQQPGAELVKPGASLKMSCKAS	25	26
27-38	CDR-H1	GYTFTSYN	8	12
39-55	HFR2	LHWVKQTPGQDLEWIGA	17	17
56-65	CDR-H2	IYPGNGDT	8	10
66-104	HFR3	SYNQKFKGKATLTVDKSSSTAYMQLSSLTSEDSAVYYC	38	39
105-117	CDR-H3	ARLGLRRGFDV	11	13
118-128	HFR4	WGAGTTVTVSS	11	11

Entry: N422/18.1

Protein Target: GluN2C/NR2C glutamate receptor

Category: NeuroMab mAbs

Mouse Light Chain Results

Mouse Heavy Chain Results