NeuroMabSeq

Mouse Light Chain Results

Sequence: 1 -- Star rating: ☆4.67 -- Verified by Cloning: ✅

ACTTATGAGAATAGCAGTAATTAGCTAGGGACCAAAATTCAAAGACAAAATGCATTTTCAAGTGCAGATTTTCAGCTTCCTGCTAATCAGTGCCTCAGTCATAATGTCCAGAGGACAAATTGTTCTCACCCAGTCTCCAGCAATCATGTCTGCATCTCCAGGGGAGAAGGTCACCATAACCTGCAGTGCCAGCTCAATTGTAACTTACATGCACTGGTTCCAGCAGAAGCCAGGCACTTCTCCCAAACTCTGGATTTATAGCACATCCTACCTGGCTTCTGGAGTCCCTGCTCGGTTCAGTGGCAGTGGATCTGGGATGTCTTACTCTCTCACAATCAGCCGAATGGAGGCTGAAGATGCTGCCACTTATTACTGCCAGCAAAGGAGTACTTACCCGTACACGTTCGGAGGGGGGACCAAGCTGGAAGTAAAACGGGCT

Sequence 1 corresponding to IMGT amino acids 1-127:

CAAATTGTTCTCACCCAGTCTCCAGCAATCATGTCTGCATCTCCAGGGGAGAAGGTCACCATAACCTGCAGTGCCAGCTCAATTGTAACTTACATGCACTGGTTCCAGCAGAAGCCAGGCACTTCTCCCAAACTCTGGATTTATAGCACATCCTACCTGGCTTCTGGAGTCCCTGCTCGGTTCAGTGGCAGTGGATCTGGGATGTCTTACTCTCTCACAATCAGCCGAATGGAGGCTGAAGATGCTGCCACTTATTACTGCCAGCAAAGGAGTACTTACCCGTACACGTTCGGAGGGGGGACCAAGCTGGAAGTAAAA

Sequencing Info ☆ Scoring Info Amino Acid Information Blat Sequence

IMGT amino acid positions:

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	101	102	103	104	105	106	107	108	109	110	111	112	113	114	115	116	117	118	119	120	121	122	123	124	125	126	127
Q	I	V	L	T	Q	S	P	A	I	M	S	A	S	P	G	E	K	V	T	I	T	C	S	A	S	S	I	V	-	-	-	-	-	-	-	T	Y	M	H	W	F	Q	Q	K	P	G	T	S	P	K	L	W	I	Y	S	T	-	-	-	-	-	-	-	S	Y	L	A	S	G	V	P	-	A	R	F	S	G	S	G	-	-	S	G	M	S	Y	S	L	T	I	S	R	M	E	A	E	D	A	A	T	Y	Y	C	Q	Q	R	S	T	-	-	-	-	Y	P	Y	T	F	G	G	G	T	K	L	E	V	K
LFR1																										CDR-L1												LFR2																	CDR-L2										LFR3																																							CDR-L3													LFR4

Residues	Region	Sequence Fragment	Length	Max Index Range
1-26	LFR1	QIVLTQSPAIMSASPGEKVTITCSAS	26	26
27-38	CDR-L1	SIVTY	5	12
39-55	LFR2	MHWFQQKPGTSPKLWIY	17	17
56-65	CDR-L2	STS	3	10
66-104	LFR3	YLASGVPARFSGSGSGMSYSLTISRMEAEDAATYYC	36	39
105-117	CDR-L3	QQRSTYPYT	9	13
118-128	LFR4	FGGGTKLEVK	10	10

Mouse Heavy Chain Results

Sequence: 1 -- Star rating: ☆4.52 -- Verified by Cloning: ✅

AGGCAGAGAACTTTAGCCCTGTCTTCTTTTTTAGTGTTCAGCACTGACAATATGACATTGAACATGCTGTTGGGGCTGAAGTGGGTTTTCTTTGTTGTTTTTTATCAAGGTGTGCATTGTGAGGTGCACCTTGTTGAGTCTGGTGGAGGATTGGTGCAGCCTAAAGGGTCATTGAAACTCTCATGTGCAGCCTCTGGATTCACCTTCAATACCAACGCCATGAACTGGGTCCGCCAGGCTCCAGGAAAGGGTTTGGAATGGGTTGCTCGCATAAGAAGTAAAAGTAATAATTATGCAACATATTATGCCGATTCAGTGAAAGACAGGTTCACCATCTCCAGAGATGATTCACAAAACATGCTCTATCTGCAAATGAACAACTTGAAAACTGAGGACACAGCCATGTATTACTGTGTGAGGGATTACTACGGCCCTTATAGTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG

Sequence 1 corresponding to IMGT amino acids 1-128:

GAGGTGCACCTTGTTGAGTCTGGTGGAGGATTGGTGCAGCCTAAAGGGTCATTGAAACTCTCATGTGCAGCCTCTGGATTCACCTTCAATACCAACGCCATGAACTGGGTCCGCCAGGCTCCAGGAAAGGGTTTGGAATGGGTTGCTCGCATAAGAAGTAAAAGTAATAATTATGCAACATATTATGCCGATTCAGTGAAAGACAGGTTCACCATCTCCAGAGATGATTCACAAAACATGCTCTATCTGCAAATGAACAACTTGAAAACTGAGGACACAGCCATGTATTACTGTGTGAGGGATTACTACGGCCCTTATAGTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCA

Sequencing Info ☆ Scoring Info Amino Acid Information Blat Sequence

IMGT amino acid positions:

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	101	102	103	104	105	106	107	108	109	110	111	112	113	114	115	116	117	118	119	120	121	122	123	124	125	126	127	128
E	V	H	L	V	E	S	G	G	-	G	L	V	Q	P	K	G	S	L	K	L	S	C	A	A	S	G	F	T	F	-	-	-	-	N	T	N	A	M	N	W	V	R	Q	A	P	G	K	G	L	E	W	V	A	R	I	R	S	K	S	N	N	Y	A	T	Y	Y	A	D	S	V	K	-	D	R	F	T	I	S	R	D	D	S	Q	N	M	L	Y	L	Q	M	N	N	L	K	T	E	D	T	A	M	Y	Y	C	V	R	D	Y	Y	G	-	P	Y	S	M	D	Y	W	G	Q	G	T	S	V	T	V	S	S
HFR1																										CDR-H1												HFR2																	CDR-H2										HFR3																																							CDR-H3													HFR4

Residues	Region	Sequence Fragment	Length	Max Index Range
1-26	HFR1	EVHLVESGGGLVQPKGSLKLSCAAS	25	26
27-38	CDR-H1	GFTFNTNA	8	12
39-55	HFR2	MNWVRQAPGKGLEWVAR	17	17
56-65	CDR-H2	IRSKSNNYAT	10	10
66-104	HFR3	YYADSVKDRFTISRDDSQNMLYLQMNNLKTEDTAMYYC	38	39
105-117	CDR-H3	VRDYYGPYSMDY	12	13
118-128	HFR4	WGQGTSVTVSS	11	11

Entry: N367/51.1

Protein Target: Shank1 and Shank3

Category: NeuroMab mAbs

Mouse Light Chain Results

Mouse Heavy Chain Results