NeuroMabSeq

Mouse Light Chain Results

Sequence: 1 -- Star rating: ☆4.93 -- Verified by Cloning: ✅

CTACATCTGAAAGGCAGGTGGAGCAAGATGGAATCACAGACTCAGGTCCTCATCTCCTTGCTGTTCTGGGTATCTGGTACCTGTGGGGACATTATGATGACACAGTCTCCATCCTCCCTGAGTGTGTCAGCAGGAGAGAAGGTCACTCTGAGCTGCAAGTCCAGTCAGAGTCTGTTAAACAGTGGAAGTCAAATGAACTACTTGGCCTGGTACCAGCAGAAACCAGGGCAGCCTCCTGAACTGTTGATCTACGGGGCATCCACTAGGAGATCTGGGGTCCCTGATCGCTTCACAGGCAGTGGATCTGGAACCGATTTCACTCTTACCATCAGCAGTGTGCAGGCTGAAGACCTGGCAGTTTATTACTGTCAGAATGATCATAGTTATCCGCTCACGTTCGGTGCTGGGACCAAGCTGGAGCTGAAACGGGCT

Sequence 1 corresponding to IMGT amino acids 1-127:

GACATTATGATGACACAGTCTCCATCCTCCCTGAGTGTGTCAGCAGGAGAGAAGGTCACTCTGAGCTGCAAGTCCAGTCAGAGTCTGTTAAACAGTGGAAGTCAAATGAACTACTTGGCCTGGTACCAGCAGAAACCAGGGCAGCCTCCTGAACTGTTGATCTACGGGGCATCCACTAGGAGATCTGGGGTCCCTGATCGCTTCACAGGCAGTGGATCTGGAACCGATTTCACTCTTACCATCAGCAGTGTGCAGGCTGAAGACCTGGCAGTTTATTACTGTCAGAATGATCATAGTTATCCGCTCACGTTCGGTGCTGGGACCAAGCTGGAGCTGAAA

Sequencing Info ☆ Scoring Info Amino Acid Information Blat Sequence

IMGT amino acid positions:

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	101	102	103	104	105	106	107	108	109	110	111	112	113	114	115	116	117	118	119	120	121	122	123	124	125	126	127
D	I	M	M	T	Q	S	P	S	S	L	S	V	S	A	G	E	K	V	T	L	S	C	K	S	S	Q	S	L	L	N	S	G	S	Q	M	N	Y	L	A	W	Y	Q	Q	K	P	G	Q	P	P	E	L	L	I	Y	G	A	-	-	-	-	-	-	-	S	T	R	R	S	G	V	P	-	D	R	F	T	G	S	G	-	-	S	G	T	D	F	T	L	T	I	S	S	V	Q	A	E	D	L	A	V	Y	Y	C	Q	N	D	H	S	-	-	-	-	Y	P	L	T	F	G	A	G	T	K	L	E	L	K
LFR1																										CDR-L1												LFR2																	CDR-L2										LFR3																																							CDR-L3													LFR4

Residues	Region	Sequence Fragment	Length	Max Index Range
1-26	LFR1	DIMMTQSPSSLSVSAGEKVTLSCKSS	26	26
27-38	CDR-L1	QSLLNSGSQMNY	12	12
39-55	LFR2	LAWYQQKPGQPPELLIY	17	17
56-65	CDR-L2	GAS	3	10
66-104	LFR3	TRRSGVPDRFTGSGSGTDFTLTISSVQAEDLAVYYC	36	39
105-117	CDR-L3	QNDHSYPLT	9	13
118-128	LFR4	FGAGTKLELK	10	10

Mouse Heavy Chain Results

Sequence: 1 -- Star rating: ☆5.00 -- Verified by Cloning: ✅

AGCTCTGACAGAGGAGGCCAGTCCTGGAATTGATTCCCAGTTCCTCACGTTCAGTGATGAGCAGTGAACACAGACCCCTCACCATGAACTTCGGGCTCAGATTGATTTTCCTTGTCCTTACTTTAAAAGGTGTCCAGTGTGACGTGAAACTGGTGGAGTCTGGGGGAGGCTTAGTGAAGCCTGGAGGGTCCCTGAAACTCTCCTGTGCAGCCTCTGGATTCACTTTCAGTAACTATACCATGTCTTGGGTTCGCCAGACTCCGGAAAAGGGGCTGGAGTGGGTCGCAACCATTAGTACTGGTGGTAGTTACACCTATTATCCAGACAGTGTGAAGGGCCGATTCACCATCTCCAGAGACAATGCCAAGAACACCCTGTACCTGCAAATGAGCAGTCTGAAGTCTGAGGACACAGCCATATACTACTGTACAAGAGATGGGGATGGTAACTACGCGTGGTTTGCTTACTGGGGCCAAGGGACTCAGGTCACTGTCTCTGCAG

Sequence 1 corresponding to IMGT amino acids 1-128:

GACGTGAAACTGGTGGAGTCTGGGGGAGGCTTAGTGAAGCCTGGAGGGTCCCTGAAACTCTCCTGTGCAGCCTCTGGATTCACTTTCAGTAACTATACCATGTCTTGGGTTCGCCAGACTCCGGAAAAGGGGCTGGAGTGGGTCGCAACCATTAGTACTGGTGGTAGTTACACCTATTATCCAGACAGTGTGAAGGGCCGATTCACCATCTCCAGAGACAATGCCAAGAACACCCTGTACCTGCAAATGAGCAGTCTGAAGTCTGAGGACACAGCCATATACTACTGTACAAGAGATGGGGATGGTAACTACGCGTGGTTTGCTTACTGGGGCCAAGGGACTCAGGTCACTGTCTCTGCA

Sequencing Info ☆ Scoring Info Amino Acid Information Blat Sequence

IMGT amino acid positions:

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	101	102	103	104	105	106	107	108	109	110	111	112	113	114	115	116	117	118	119	120	121	122	123	124	125	126	127	128
D	V	K	L	V	E	S	G	G	-	G	L	V	K	P	G	G	S	L	K	L	S	C	A	A	S	G	F	T	F	-	-	-	-	S	N	Y	T	M	S	W	V	R	Q	T	P	E	K	G	L	E	W	V	A	T	I	S	T	G	-	-	G	S	Y	T	Y	Y	P	D	S	V	K	-	G	R	F	T	I	S	R	D	N	A	K	N	T	L	Y	L	Q	M	S	S	L	K	S	E	D	T	A	I	Y	Y	C	T	R	D	G	D	G	N	Y	A	W	F	A	Y	W	G	Q	G	T	Q	V	T	V	S	A
HFR1																										CDR-H1												HFR2																	CDR-H2										HFR3																																							CDR-H3													HFR4

Residues	Region	Sequence Fragment	Length	Max Index Range
1-26	HFR1	DVKLVESGGGLVKPGGSLKLSCAAS	25	26
27-38	CDR-H1	GFTFSNYT	8	12
39-55	HFR2	MSWVRQTPEKGLEWVAT	17	17
56-65	CDR-H2	ISTGGSYT	8	10
66-104	HFR3	YYPDSVKGRFTISRDNAKNTLYLQMSSLKSEDTAIYYC	38	39
105-117	CDR-H3	TRDGDGNYAWFAY	13	13
118-128	HFR4	WGQGTQVTVSA	11	11

Entry: K47/42.1

Protein Target: Kvbeta1.2 K+ channel

Category: NeuroMab mAbs

Mouse Light Chain Results

Mouse Heavy Chain Results