NeuroMabSeq

Mouse Light Chain Results

Sequence: 1 -- Star rating: ☆1.19 -- Verified by Cloning: ✅

AGCAGAGATCAGTAGTACCTGCATTATGGCCTGGACTCCTCTCTTCTTCTTCTTTGTTCTTCATTGCTCAGGTTCTTTCTCCCAACTTATGCTCACTCAGTCATCTTCAGCCTCTTTCTCCCTGGGAGCCTCAGCAAAACTCACGTGCACCTTGAGTAGTCAGCACAGTACGTACACCATTGAATGGTATCAGCAACAGCCACTCAAGCCTCCTAAGTTTGTGATGGACCTTAAGAAAGATGGAAGCCACAGCACAGGTGATGGGATTCCTGATCGCTTCTCTGGATCCAGCTCTGGTGCTGATCGCTACCTTAGCATTTCCAACATCCAGCCTGAAGATGAAGCAATATACATCTGTGGTGTGGGTGATACAATTAAGGAACAATTTGTGTATGTTTTCGGCGGTGGCACCAAGGTCACTGTCCTAGGTCAGCCCAAGTCCACTCCCACTCTCACCGTGTTTCCACCTTCCTCTGAGGAGCTCAAGGAAAACAAA

Sequence 1 corresponding to IMGT amino acids 1-127:

CAACTTATGCTCACTCAGTCATCTTCAGCCTCTTTCTCCCTGGGAGCCTCAGCAAAACTCACGTGCACCTTGAGTAGTCAGCACAGTACGTACACCATTGAATGGTATCAGCAACAGCCACTCAAGCCTCCTAAGTTTGTGATGGACCTTAAGAAAGATGGAAGCCACAGCACAGGTGATGGGATTCCTGATCGCTTCTCTGGATCCAGCTCTGGTGCTGATCGCTACCTTAGCATTTCCAACATCCAGCCTGAAGATGAAGCAATATACATCTGTGGTGTGGGTGATACAATTAAGGAACAATTTGTGTATGTTTTCGGCGGTGGCACCAAGGTCACTGTCCTA

Sequencing Info ☆ Scoring Info Amino Acid Information Blat Sequence

IMGT amino acid positions:

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	101	102	103	104	105	106	107	108	109	110	111	112	113	114	115	116	117	118	119	120	121	122	123	124	125	126	127
Q	L	M	L	T	Q	S	S	S	-	A	S	F	S	L	G	A	S	A	K	L	T	C	T	L	S	S	Q	H	S	-	-	-	-	-	T	Y	T	I	E	W	Y	Q	Q	Q	P	L	K	P	P	K	F	V	M	D	L	K	K	D	-	-	-	G	S	H	S	T	G	D	G	I	P	-	D	R	F	S	G	S	S	-	-	S	G	A	D	R	Y	L	S	I	S	N	I	Q	P	E	D	E	A	I	Y	I	C	G	V	G	D	T	I	K	E	Q	F	V	Y	V	F	G	G	G	T	K	V	T	V	L
LFR1																										CDR-L1												LFR2																	CDR-L2										LFR3																																							CDR-L3													LFR4

Residues	Region	Sequence Fragment	Length	Max Index Range
1-26	LFR1	QLMLTQSSSASFSLGASAKLTCTLS	25	26
27-38	CDR-L1	SQHSTYT	7	12
39-55	LFR2	IEWYQQQPLKPPKFVMD	17	17
56-65	CDR-L2	LKKDGSH	7	10
66-104	LFR3	STGDGIPDRFSGSSSGADRYLSISNIQPEDEAIYIC	36	39
105-117	CDR-L3	GVGDTIKEQFVYV	13	13
118-128	LFR4	FGGGTKVTVL	10	10

Mouse Heavy Chain Results

Sequence: 1 -- Star rating: ☆2.00 -- Verified by Cloning: ✅

AGCTCTGACAGAGGAGGCCAGTCCTGGATTTGAGTTCCTCACATTCAGTGATGAGCACTGAACACGGACCCCTCACCATGAATTTCGGGCTCAGCTTGATTTTCCTTGTCCTTGTTTTAAAAGGTGTCCTGTGTGAAGTGAAGCTGGTGGAGTCTGGGGGAGGTTTAGTGCAGCCTGGAGGGTCCCTGAAACTCTACTGTGCAGCCTCTGGATTCAGTTTCAGTACCTATACCATGTCTTGGGTTCGCCAGACTCCAGAGAAGAGGCTGGAGTGGGTCGCATACATTAGTAAAAGTGGTGCCATCACCTATTATTCAGACACTGTAAAGGGCCGATTCACCATCTCCAGAGACAATACCATGAACACCCTGTACCTGCAAATGAGCAGTCTGAAGTCTGAGGACACGGCCATGTATTACTGTGCAAGACATCCCCTCATACTCGAATATTATAGTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG

Sequence 1 corresponding to IMGT amino acids 1-128:

GAAGTGAAGCTGGTGGAGTCTGGGGGAGGTTTAGTGCAGCCTGGAGGGTCCCTGAAACTCTACTGTGCAGCCTCTGGATTCAGTTTCAGTACCTATACCATGTCTTGGGTTCGCCAGACTCCAGAGAAGAGGCTGGAGTGGGTCGCATACATTAGTAAAAGTGGTGCCATCACCTATTATTCAGACACTGTAAAGGGCCGATTCACCATCTCCAGAGACAATACCATGAACACCCTGTACCTGCAAATGAGCAGTCTGAAGTCTGAGGACACGGCCATGTATTACTGTGCAAGACATCCCCTCATACTCGAATATTATAGTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCA

Sequencing Info ☆ Scoring Info Amino Acid Information Blat Sequence

IMGT amino acid positions:

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	101	102	103	104	105	106	107	108	109	110	111	112	112	113	114	115	116	117	118	119	120	121	122	123	124	125	126	127	128
E	V	K	L	V	E	S	G	G	-	G	L	V	Q	P	G	G	S	L	K	L	Y	C	A	A	S	G	F	S	F	-	-	-	-	S	T	Y	T	M	S	W	V	R	Q	T	P	E	K	R	L	E	W	V	A	Y	I	S	K	S	-	-	G	A	I	T	Y	Y	S	D	T	V	K	-	G	R	F	T	I	S	R	D	N	T	M	N	T	L	Y	L	Q	M	S	S	L	K	S	E	D	T	A	M	Y	Y	C	A	R	H	P	L	I	L	E	Y	Y	S	M	D	Y	W	G	Q	G	T	S	V	T	V	S	S
HFR1																										CDR-H1												HFR2																	CDR-H2										HFR3																																							CDR-H3														HFR4

Residues	Region	Sequence Fragment	Length	Max Index Range
1-26	HFR1	EVKLVESGGGLVQPGGSLKLYCAAS	25	26
27-38	CDR-H1	GFSFSTYT	8	12
39-55	HFR2	MSWVRQTPEKRLEWVAY	17	17
56-65	CDR-H2	ISKSGAIT	8	10
66-104	HFR3	YYSDTVKGRFTISRDNTMNTLYLQMSSLKSEDTAMYYC	38	39
105-117	CDR-H3	ARHPLILEYYSMDY	14	14
118-128	HFR4	WGQGTSVTVSS	11	11

Entry: N123/48.1

Protein Target: Histone H3-pThr11

Category: NeuroMab mAbs

Mouse Light Chain Results

Mouse Heavy Chain Results