NeuroMabSeq

Mouse Light Chain Results

Sequence: 1 -- Star rating: ☆4.64

GAGCCACACAAACTCAGGGAAAGCTCGAAGATGGTTTTCACACCTCAGATACTTGGACTTATGCTTTTTTGGATTTCAGCCTCCAGAGGTGATATTGTGCTAACTCAGTCTCCAGCCACCCTGTCTGTGACTCCAGGAGATAGCGTCAGTCTTTCCTGCAGGGCCAGCCAAAGTATTAGCAACAACCTACACTGGTATCAACAAAAATCACATGAGTCTCCAAGGCTTCTCATCAAGTATGCTTCCCAGTCCATCTCTGGGATCCCCTCCAGGTTCAGTGGCAGTGGATCAGGGACAGATTTCACTCTCAGTATCAACAGTGTGGAGACTGAAGATTTTGGAATGTATTTCTGTCAACAGAGTAACAGCTGGCCGCTCACGTTCGGTGCTGGGACCAAGCTGGAGCTGAAACGGGCT

Sequence 1 corresponding to IMGT amino acids 1-127:

GATATTGTGCTAACTCAGTCTCCAGCCACCCTGTCTGTGACTCCAGGAGATAGCGTCAGTCTTTCCTGCAGGGCCAGCCAAAGTATTAGCAACAACCTACACTGGTATCAACAAAAATCACATGAGTCTCCAAGGCTTCTCATCAAGTATGCTTCCCAGTCCATCTCTGGGATCCCCTCCAGGTTCAGTGGCAGTGGATCAGGGACAGATTTCACTCTCAGTATCAACAGTGTGGAGACTGAAGATTTTGGAATGTATTTCTGTCAACAGAGTAACAGCTGGCCGCTCACGTTCGGTGCTGGGACCAAGCTGGAGCTGAAA

Sequencing Info ☆ Scoring Info Amino Acid Information Blat Sequence

IMGT amino acid positions:

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	101	102	103	104	105	106	107	108	109	110	111	112	113	114	115	116	117	118	119	120	121	122	123	124	125	126	127
D	I	V	L	T	Q	S	P	A	T	L	S	V	T	P	G	D	S	V	S	L	S	C	R	A	S	Q	S	I	-	-	-	-	-	-	S	N	N	L	H	W	Y	Q	Q	K	S	H	E	S	P	R	L	L	I	K	Y	A	-	-	-	-	-	-	-	S	Q	S	I	S	G	I	P	-	S	R	F	S	G	S	G	-	-	S	G	T	D	F	T	L	S	I	N	S	V	E	T	E	D	F	G	M	Y	F	C	Q	Q	S	N	S	-	-	-	-	W	P	L	T	F	G	A	G	T	K	L	E	L	K
LFR1																										CDR-L1												LFR2																	CDR-L2										LFR3																																							CDR-L3													LFR4

Residues	Region	Sequence Fragment	Length	Max Index Range
1-26	LFR1	DIVLTQSPATLSVTPGDSVSLSCRAS	26	26
27-38	CDR-L1	QSISNN	6	12
39-55	LFR2	LHWYQQKSHESPRLLIK	17	17
56-65	CDR-L2	YAS	3	10
66-104	LFR3	QSISGIPSRFSGSGSGTDFTLSINSVETEDFGMYFC	36	39
105-117	CDR-L3	QQSNSWPLT	9	13
118-128	LFR4	FGAGTKLELK	10	10

Mouse Heavy Chain Results

Sequence: 1 -- Star rating: ☆4.45

AGCTCTGACAGAGGAGGCCAGTCCTGGAATTGATTCCCAGTTCCTCACGTTCAGTGATGAGCAGTGAACACAGACCCCTCACCATGAACTTCGGGCTCAGATTGATTTTCCTTGTCCTTACTTTAAAAGGTGTCCAGTGTGACGTGAAGCTGGTGGAGTCTGGGGGAGGCTTAGTGAAGCCTGGAGGGTCCCTGAAACTCTCCTGTGCAGCCTCTGGATTCACTTTCAGTAGCTATACCATGTCTTGGGTTCGCCAGACTCCGGAGAAGAGGCTGGAGTGGGTCGCAACCATTAGTAGTGGTGGTAGTTACACCTACTATCCAGACAGTGTGAAGGGCCGATTCACCATCTCCAGAGACAATGCCAAGAACACCCTGTACCTGCAAATGAGCAGTCTGAAGTCTGAGGACACAGCCATGTATTACTGTACAACGTATGGTAACTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG

Sequence 1 corresponding to IMGT amino acids 1-128:

GACGTGAAGCTGGTGGAGTCTGGGGGAGGCTTAGTGAAGCCTGGAGGGTCCCTGAAACTCTCCTGTGCAGCCTCTGGATTCACTTTCAGTAGCTATACCATGTCTTGGGTTCGCCAGACTCCGGAGAAGAGGCTGGAGTGGGTCGCAACCATTAGTAGTGGTGGTAGTTACACCTACTATCCAGACAGTGTGAAGGGCCGATTCACCATCTCCAGAGACAATGCCAAGAACACCCTGTACCTGCAAATGAGCAGTCTGAAGTCTGAGGACACAGCCATGTATTACTGTACAACGTATGGTAACTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCA

Sequencing Info ☆ Scoring Info Amino Acid Information Blat Sequence

IMGT amino acid positions:

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	101	102	103	104	105	106	107	108	109	110	111	112	113	114	115	116	117	118	119	120	121	122	123	124	125	126	127	128
D	V	K	L	V	E	S	G	G	-	G	L	V	K	P	G	G	S	L	K	L	S	C	A	A	S	G	F	T	F	-	-	-	-	S	S	Y	T	M	S	W	V	R	Q	T	P	E	K	R	L	E	W	V	A	T	I	S	S	G	-	-	G	S	Y	T	Y	Y	P	D	S	V	K	-	G	R	F	T	I	S	R	D	N	A	K	N	T	L	Y	L	Q	M	S	S	L	K	S	E	D	T	A	M	Y	Y	C	T	T	Y	G	N	-	-	-	-	Y	F	D	Y	W	G	Q	G	T	T	L	T	V	S	S
HFR1																										CDR-H1												HFR2																	CDR-H2										HFR3																																							CDR-H3													HFR4

Residues	Region	Sequence Fragment	Length	Max Index Range
1-26	HFR1	DVKLVESGGGLVKPGGSLKLSCAAS	25	26
27-38	CDR-H1	GFTFSSYT	8	12
39-55	HFR2	MSWVRQTPEKRLEWVAT	17	17
56-65	CDR-H2	ISSGGSYT	8	10
66-104	HFR3	YYPDSVKGRFTISRDNAKNTLYLQMSSLKSEDTAMYYC	38	39
105-117	CDR-H3	TTYGNYFDY	9	13
118-128	HFR4	WGQGTTLTVSS	11	11

Entry: N422/76.1

Protein Target: GluN2C/NR2C glutamate receptor

Category: Non-NeuroMab mAbs

Mouse Light Chain Results

Mouse Heavy Chain Results