NeuroMabSeq

Mouse Light Chain Results

Sequence: 1 -- Star rating: ☆3.78

ACTGATCACTCTCCTATGTTCATTTCCTCAAAATGATGAGTCCTGCCCAGTTCCTGTTTCTGTTAGTGCTCTGGATTCGGGAAACCAACGGTGATGTTGTGATGACCCAGACTCCACTCACTTTGTCGGTTACCATTGGACAACCAGCCTCCATCTCTTGCAAGTCAAGTCAGAGCCTCTTAGATAGTTATGGAAAGACATATTTGAATTGGTTGTTACAGAGGCCAGGCCAGTCTCCAAAGCGCCTAATCTATCTGGTGTCTAAACTGGACTCTGGAGTCCCTGACAGGTTCACTGGCAGTGGATCAGGGACAGATTTCACACTGAAAATCAGCAGAGTGGAGGCTGAGGATTTGGGAGTTTATTATTGCTGGCAAGGTACACATTTTCCTCACACGTTCGGAGGGGGGACCAAGCTGGAAATAAAACGGGCT

Sequence 1 corresponding to IMGT amino acids 1-127:

GATGTTGTGATGACCCAGACTCCACTCACTTTGTCGGTTACCATTGGACAACCAGCCTCCATCTCTTGCAAGTCAAGTCAGAGCCTCTTAGATAGTTATGGAAAGACATATTTGAATTGGTTGTTACAGAGGCCAGGCCAGTCTCCAAAGCGCCTAATCTATCTGGTGTCTAAACTGGACTCTGGAGTCCCTGACAGGTTCACTGGCAGTGGATCAGGGACAGATTTCACACTGAAAATCAGCAGAGTGGAGGCTGAGGATTTGGGAGTTTATTATTGCTGGCAAGGTACACATTTTCCTCACACGTTCGGAGGGGGGACCAAGCTGGAAATAAAA

Sequencing Info ☆ Scoring Info Amino Acid Information Blat Sequence

IMGT amino acid positions:

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	101	102	103	104	105	106	107	108	109	110	111	112	113	114	115	116	117	118	119	120	121	122	123	124	125	126	127
D	V	V	M	T	Q	T	P	L	T	L	S	V	T	I	G	Q	P	A	S	I	S	C	K	S	S	Q	S	L	L	D	S	-	Y	G	K	T	Y	L	N	W	L	L	Q	R	P	G	Q	S	P	K	R	L	I	Y	L	V	-	-	-	-	-	-	-	S	K	L	D	S	G	V	P	-	D	R	F	T	G	S	G	-	-	S	G	T	D	F	T	L	K	I	S	R	V	E	A	E	D	L	G	V	Y	Y	C	W	Q	G	T	H	-	-	-	-	F	P	H	T	F	G	G	G	T	K	L	E	I	K
LFR1																										CDR-L1												LFR2																	CDR-L2										LFR3																																							CDR-L3													LFR4

Residues	Region	Sequence Fragment	Length	Max Index Range
1-26	LFR1	DVVMTQTPLTLSVTIGQPASISCKSS	26	26
27-38	CDR-L1	QSLLDSYGKTY	11	12
39-55	LFR2	LNWLLQRPGQSPKRLIY	17	17
56-65	CDR-L2	LVS	3	10
66-104	LFR3	KLDSGVPDRFTGSGSGTDFTLKISRVEAEDLGVYYC	36	39
105-117	CDR-L3	WQGTHFPHT	9	13
118-128	LFR4	FGGGTKLEIK	10	10

Mouse Heavy Chain Results

Sequence: 1 -- Star rating: ☆5.00

AGATCACAGTAGTCTCTACAGTCACAGGAGTACACAGGGCATTGCCATGGGTTGGAGCTGTATCATCTTCTTTCTGGTAGCAACAGCTACAGGTGTGCACTCCCAGGTCCAGCTGCAGCAGTCTGGGCCTGAGGTGGTGAGGCCTGGGGTCTCAGTGAAGATTTCCTGCAAGGGTTCCGGCTACACATTCACTGATTATGCTATGCACTGGGTGAAGCAGAGTCATGGAAAGAGTCTAGAGTGGATTGGAGTTATTAGTACTTACAATGATAATACAAAGTACAACCAGAAGTTTAAGGGCAAGGCCACAATGACTGTAGACAAATCCTCCAGCACAGCCTATATGGAACTTGCCAGATTGACATCTGAGGATTCTGCCATCTATTACTGTGCAAGAGGGGGGGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG

Sequence 1 corresponding to IMGT amino acids 1-128:

CAGGTCCAGCTGCAGCAGTCTGGGCCTGAGGTGGTGAGGCCTGGGGTCTCAGTGAAGATTTCCTGCAAGGGTTCCGGCTACACATTCACTGATTATGCTATGCACTGGGTGAAGCAGAGTCATGGAAAGAGTCTAGAGTGGATTGGAGTTATTAGTACTTACAATGATAATACAAAGTACAACCAGAAGTTTAAGGGCAAGGCCACAATGACTGTAGACAAATCCTCCAGCACAGCCTATATGGAACTTGCCAGATTGACATCTGAGGATTCTGCCATCTATTACTGTGCAAGAGGGGGGGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCA

Sequencing Info ☆ Scoring Info Amino Acid Information Blat Sequence

IMGT amino acid positions:

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	101	102	103	104	105	106	107	108	109	110	111	112	113	114	115	116	117	118	119	120	121	122	123	124	125	126	127	128
Q	V	Q	L	Q	Q	S	G	P	-	E	V	V	R	P	G	V	S	V	K	I	S	C	K	G	S	G	Y	T	F	-	-	-	-	T	D	Y	A	M	H	W	V	K	Q	S	H	G	K	S	L	E	W	I	G	V	I	S	T	Y	-	-	N	D	N	T	K	Y	N	Q	K	F	K	-	G	K	A	T	M	T	V	D	K	S	S	S	T	A	Y	M	E	L	A	R	L	T	S	E	D	S	A	I	Y	Y	C	A	R	G	-	-	-	-	-	-	-	G	A	Y	W	G	Q	G	T	L	V	T	V	S	A
HFR1																										CDR-H1												HFR2																	CDR-H2										HFR3																																							CDR-H3													HFR4

Residues	Region	Sequence Fragment	Length	Max Index Range
1-26	HFR1	QVQLQQSGPEVVRPGVSVKISCKGS	25	26
27-38	CDR-H1	GYTFTDYA	8	12
39-55	HFR2	MHWVKQSHGKSLEWIGV	17	17
56-65	CDR-H2	ISTYNDNT	8	10
66-104	HFR3	KYNQKFKGKATMTVDKSSSTAYMELARLTSEDSAIYYC	38	39
105-117	CDR-H3	ARGGAY	6	13
118-128	HFR4	WGQGTLVTVSA	11	11

Entry: N59/36.1

Protein Target: GluN2B/NR2B glutamate receptor

Category: NeuroMab mAbs

Mouse Light Chain Results

Mouse Heavy Chain Results