NeuroMabSeq

Mouse Light Chain Results

Sequence: 1 -- Star rating: ☆4.90 -- Verified by Cloning: ✅

GAAATACATCAGACCAGCATGGGCTTCAAGATGGAGTCTCATACTCAGGCCTTTGTATTCGCGTTTCTCTGGTTGTCTGGTGTTGATGGAGACATTGTGATGACCCAGTCTCAAAAATTCATGTCCACATCAGTAGGAGACAGGCTCAGCATCATCTGCAAGGCCAGTCAGAATGTGGGTACTGCTGTAGCCTGGTATCAACAGAAACCAGGACAATCTCCTAAATTACTGATTTACTCGGCATCCAATCGGTACACTGGAGTCCCTGATCGCTTCACAGGCAGTGGATCTGGGACAGATTTCACTCTCACCATCAGCAATATGCAGTCTGAAGACCTGGCAGATTATTTCTGCCAGCAATATAACAACTATCCTCTAACGTTCGGCTCGGGGACAAGGTTGGATATAAAACGGGCT

Sequence 1 corresponding to IMGT amino acids 1-127:

GACATTGTGATGACCCAGTCTCAAAAATTCATGTCCACATCAGTAGGAGACAGGCTCAGCATCATCTGCAAGGCCAGTCAGAATGTGGGTACTGCTGTAGCCTGGTATCAACAGAAACCAGGACAATCTCCTAAATTACTGATTTACTCGGCATCCAATCGGTACACTGGAGTCCCTGATCGCTTCACAGGCAGTGGATCTGGGACAGATTTCACTCTCACCATCAGCAATATGCAGTCTGAAGACCTGGCAGATTATTTCTGCCAGCAATATAACAACTATCCTCTAACGTTCGGCTCGGGGACAAGGTTGGATATAAAA

Sequencing Info ☆ Scoring Info Amino Acid Information Blat Sequence

IMGT amino acid positions:

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	101	102	103	104	105	106	107	108	109	110	111	112	113	114	115	116	117	118	119	120	121	122	123	124	125	126	127
D	I	V	M	T	Q	S	Q	K	F	M	S	T	S	V	G	D	R	L	S	I	I	C	K	A	S	Q	N	V	-	-	-	-	-	-	G	T	A	V	A	W	Y	Q	Q	K	P	G	Q	S	P	K	L	L	I	Y	S	A	-	-	-	-	-	-	-	S	N	R	Y	T	G	V	P	-	D	R	F	T	G	S	G	-	-	S	G	T	D	F	T	L	T	I	S	N	M	Q	S	E	D	L	A	D	Y	F	C	Q	Q	Y	N	N	-	-	-	-	Y	P	L	T	F	G	S	G	T	R	L	D	I	K
LFR1																										CDR-L1												LFR2																	CDR-L2										LFR3																																							CDR-L3													LFR4

Residues	Region	Sequence Fragment	Length	Max Index Range
1-26	LFR1	DIVMTQSQKFMSTSVGDRLSIICKAS	26	26
27-38	CDR-L1	QNVGTA	6	12
39-55	LFR2	VAWYQQKPGQSPKLLIY	17	17
56-65	CDR-L2	SAS	3	10
66-104	LFR3	NRYTGVPDRFTGSGSGTDFTLTISNMQSEDLADYFC	36	39
105-117	CDR-L3	QQYNNYPLT	9	13
118-128	LFR4	FGSGTRLDIK	10	10

Mouse Heavy Chain Results

Sequence: 1 -- Star rating: ☆5.00 -- Verified by Cloning: ✅

ATAAGATCACTGTTCTCTCTACAGTTACTGAGTACACAGGACCTCACCATGGGATGGAGCTGTATCATCCTCTTCTTGGTATCAACAGCTACAGGTGTCCACTCCCAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTTGTGAAGCCTGGGACTTCAGTGAGGCTGTCCTGCAAGGCTTCTGGCTACTCCTTCACCAGCTACTGGATGCACTGGGTGAAACAGAGGCCTGGACAAGGCCTTGAGTGGATCGGAGAGATTGATCCTTCTGATAGTTATTCTAACTACAATCAAAAATTCAAGGTCAAGGCCACATTGACTGTAGACAAATCCTCCACCACAGCCTACATGCAGCTCAACAGCCTGACATCTGAGGACTCTGCGGTCTATTACTGTACAAGAACGGGGAGGTACGACTGGAGTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG

Sequence 1 corresponding to IMGT amino acids 1-128:

CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTTGTGAAGCCTGGGACTTCAGTGAGGCTGTCCTGCAAGGCTTCTGGCTACTCCTTCACCAGCTACTGGATGCACTGGGTGAAACAGAGGCCTGGACAAGGCCTTGAGTGGATCGGAGAGATTGATCCTTCTGATAGTTATTCTAACTACAATCAAAAATTCAAGGTCAAGGCCACATTGACTGTAGACAAATCCTCCACCACAGCCTACATGCAGCTCAACAGCCTGACATCTGAGGACTCTGCGGTCTATTACTGTACAAGAACGGGGAGGTACGACTGGAGTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCA

Sequencing Info ☆ Scoring Info Amino Acid Information Blat Sequence

IMGT amino acid positions:

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	101	102	103	104	105	106	107	108	109	110	111	112	113	114	115	116	117	118	119	120	121	122	123	124	125	126	127	128
Q	V	Q	L	Q	Q	P	G	A	-	E	L	V	K	P	G	T	S	V	R	L	S	C	K	A	S	G	Y	S	F	-	-	-	-	T	S	Y	W	M	H	W	V	K	Q	R	P	G	Q	G	L	E	W	I	G	E	I	D	P	S	-	-	D	S	Y	S	N	Y	N	Q	K	F	K	-	V	K	A	T	L	T	V	D	K	S	S	T	T	A	Y	M	Q	L	N	S	L	T	S	E	D	S	A	V	Y	Y	C	T	R	T	G	R	Y	-	-	D	W	S	D	Y	W	G	Q	G	T	T	L	T	V	S	S
HFR1																										CDR-H1												HFR2																	CDR-H2										HFR3																																							CDR-H3													HFR4

Residues	Region	Sequence Fragment	Length	Max Index Range
1-26	HFR1	QVQLQQPGAELVKPGTSVRLSCKAS	25	26
27-38	CDR-H1	GYSFTSYW	8	12
39-55	HFR2	MHWVKQRPGQGLEWIGE	17	17
56-65	CDR-H2	IDPSDSYS	8	10
66-104	HFR3	NYNQKFKVKATLTVDKSSTTAYMQLNSLTSEDSAVYYC	38	39
105-117	CDR-H3	TRTGRYDWSDY	11	13
118-128	HFR4	WGQGTTLTVSS	11	11

Entry: N397/19.1.1

Protein Target: Nav1.5 Na+ channel

Category: NeuroMab mAbs

Mouse Light Chain Results

Mouse Heavy Chain Results