NeuroMabSeq

Mouse Light Chain Results

Sequence: 1 -- Star rating: ☆4.06

AGCATCAGACAGGCTGGGCAGCAAGATGGAATCACAGACCCAGGTCCTCATGTTTCTTCTGCTCTGGGTATCTGGTGCCTGTGCAGACATTGTGATGACACAGTCTCCATCCTCCCTGGCTATGTCAGTAGGACAGAAGGTCACTATGAGCTGCAAGTCCAGTCAGAGCCTTTTAAATAGTAGCAATCAAAAGAACTATTTGGCCTGGTACCAGCAGAAACCAGGACAGTCTCCTAAACTTCTGGTATACTTTGCATCCACTAGGGAATCTGGGGTCCCTGATCGCTTCATAGGCAGTGGATCTGGGACAGATTTCACTCTTACCATCAGCAGTGTGCAGGCTGAAGACCTGGCAGATTACTTCTGTCAGCAACATTATATCACTCCGCTCACGTTCGGTGCTGGGACCAAGCTGGAGCTGAAACGGGCT

Sequence 1 corresponding to IMGT amino acids 1-127:

GACATTGTGATGACACAGTCTCCATCCTCCCTGGCTATGTCAGTAGGACAGAAGGTCACTATGAGCTGCAAGTCCAGTCAGAGCCTTTTAAATAGTAGCAATCAAAAGAACTATTTGGCCTGGTACCAGCAGAAACCAGGACAGTCTCCTAAACTTCTGGTATACTTTGCATCCACTAGGGAATCTGGGGTCCCTGATCGCTTCATAGGCAGTGGATCTGGGACAGATTTCACTCTTACCATCAGCAGTGTGCAGGCTGAAGACCTGGCAGATTACTTCTGTCAGCAACATTATATCACTCCGCTCACGTTCGGTGCTGGGACCAAGCTGGAGCTGAAA

Sequencing Info ☆ Scoring Info Amino Acid Information Blat Sequence

IMGT amino acid positions:

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	101	102	103	104	105	106	107	108	109	110	111	112	113	114	115	116	117	118	119	120	121	122	123	124	125	126	127
D	I	V	M	T	Q	S	P	S	S	L	A	M	S	V	G	Q	K	V	T	M	S	C	K	S	S	Q	S	L	L	N	S	S	N	Q	K	N	Y	L	A	W	Y	Q	Q	K	P	G	Q	S	P	K	L	L	V	Y	F	A	-	-	-	-	-	-	-	S	T	R	E	S	G	V	P	-	D	R	F	I	G	S	G	-	-	S	G	T	D	F	T	L	T	I	S	S	V	Q	A	E	D	L	A	D	Y	F	C	Q	Q	H	Y	I	-	-	-	-	T	P	L	T	F	G	A	G	T	K	L	E	L	K
LFR1																										CDR-L1												LFR2																	CDR-L2										LFR3																																							CDR-L3													LFR4

Residues	Region	Sequence Fragment	Length	Max Index Range
1-26	LFR1	DIVMTQSPSSLAMSVGQKVTMSCKSS	26	26
27-38	CDR-L1	QSLLNSSNQKNY	12	12
39-55	LFR2	LAWYQQKPGQSPKLLVY	17	17
56-65	CDR-L2	FAS	3	10
66-104	LFR3	TRESGVPDRFIGSGSGTDFTLTISSVQAEDLADYFC	36	39
105-117	CDR-L3	QQHYITPLT	9	13
118-128	LFR4	FGAGTKLELK	10	10

Mouse Heavy Chain Results

Sequence: 1 -- Star rating: ☆3.16

AACCTATGATCAGTGTCCTCTCCACAATCTCTGAAGACACTGACTCTAACCATGGAATGGAGCTGGGTCTTTCTGTTCCTCCTGTCAGTAACTTCAGGTGTCCACTCCCAGGTCCAGCTGCAGCAGTCTGGAGCTGAGCTGGTGAAGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGACTTCTGGCTACACCTTCACCAGCTACTGGATTCAGTGGGTAAAACGGAGGCCTGGACAGGGCCTTGGGTGGATTGGAGAGATATTTCCTGGAACTGGTACTACTTACTACAATGAAAATTTCAAGGGCAAGGCCACACTGACTATAGACACATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACCTCTGAGGACTCTGCTGTCTATTTCTGTGCAAGAGTCGACGGTAGTAGCTATTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG

Sequence 1 corresponding to IMGT amino acids 1-128:

CAGGTCCAGCTGCAGCAGTCTGGAGCTGAGCTGGTGAAGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGACTTCTGGCTACACCTTCACCAGCTACTGGATTCAGTGGGTAAAACGGAGGCCTGGACAGGGCCTTGGGTGGATTGGAGAGATATTTCCTGGAACTGGTACTACTTACTACAATGAAAATTTCAAGGGCAAGGCCACACTGACTATAGACACATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACCTCTGAGGACTCTGCTGTCTATTTCTGTGCAAGAGTCGACGGTAGTAGCTATTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCA

Sequencing Info ☆ Scoring Info Amino Acid Information Blat Sequence

IMGT amino acid positions:

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	101	102	103	104	105	106	107	108	109	110	111	112	113	114	115	116	117	118	119	120	121	122	123	124	125	126	127	128
Q	V	Q	L	Q	Q	S	G	A	-	E	L	V	K	P	G	A	S	V	K	L	S	C	K	T	S	G	Y	T	F	-	-	-	-	T	S	Y	W	I	Q	W	V	K	R	R	P	G	Q	G	L	G	W	I	G	E	I	F	P	G	-	-	T	G	T	T	Y	Y	N	E	N	F	K	-	G	K	A	T	L	T	I	D	T	S	S	S	T	A	Y	M	Q	L	S	S	L	T	S	E	D	S	A	V	Y	F	C	A	R	V	D	G	S	-	-	S	Y	F	D	Y	W	G	Q	G	T	T	L	T	V	S	S
HFR1																										CDR-H1												HFR2																	CDR-H2										HFR3																																							CDR-H3													HFR4

Residues	Region	Sequence Fragment	Length	Max Index Range
1-26	HFR1	QVQLQQSGAELVKPGASVKLSCKTS	25	26
27-38	CDR-H1	GYTFTSYW	8	12
39-55	HFR2	IQWVKRRPGQGLGWIGE	17	17
56-65	CDR-H2	IFPGTGTT	8	10
66-104	HFR3	YYNENFKGKATLTIDTSSSTAYMQLSSLTSEDSAVYFC	38	39
105-117	CDR-H3	ARVDGSSYFDY	11	13
118-128	HFR4	WGQGTTLTVSS	11	11

Entry: N469/28.6

Protein Target: TWIK-2 K+ channel

Category: NeuroMab mAbs

Mouse Light Chain Results

Mouse Heavy Chain Results